ZOCOR 40 14 TAB; simvastatin, cardiovascular agents .
ACTIVE-INGREDIENT OF ZOCOR 40 14 TAB
Each tablet contains: Simvastatin 40 mg.
INDICATION OF ZOCOR 40 14 TAB
ZOCOR contains the active substance simvastatin. ZOCOR is a medicine used to lower levels of total cholestrol , “bad” cholestrol (LDL cholestrol) , and fatty substances called triglycerides in the blood . In addition , ZOCOR raises levels of “good” cholestrol ( HDL cholestrol ) . ZOCOR is a memebr of the class of medicines called statins. Cholestrol is one of several fatty substances found in the bloodstream . your total cholestrol is made up mainly of LDL and HDL cholestrol . LDL cholestrol is often called ‘ bad ‘ cholestrol because it can build up in the walls of your arteries forming plaque . eventually this plaque build-up can lead to a narrowing of the arteries this narrowing can slow or block flow to vital organs such as the heart attack and brain . this blocking of blood flow can result in a heart attack or stroke . HDL cholestrol is often called ‘good’ cholestrol because it helps keep the bad cholestrol from building up in the arteries and protects against heart disease Triglycerides are another form of fat in your blood that may increase your risk for heart disease. ZOCOR is used in addition to your cholestrol-lowering diet if you have : – a raised cholestrol level in your blood ( primary hypercholesterolaemia [ heterozygous familial and non-familial ]) or elevated fat levels in your blood ( mixed hyperlipidaemia ) . a hereditary illness ( homozygous familial hypercholestrolaemia ) that increases the cholestrol level in your blood . you may also receive other treatments . coronary heart disease (CHD) or are at high risk of CHD (because you have diabetes, history of stroke, or other blood vessel disease). ZOCOR may prolong your life by reducing the risk of heart disease problems, regardless of the amount of cholesterol in your blood. In most people, there are no immediate symptoms of high cholesterol. Your doctor can measure your cholesterol with a simple blood test. Visit your doctor regularly, keep track of your cholesterol, and discuss your goals with your doctor.
DOSAGE OF ZOCOR 40 14 TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
your doctor will determine the appropriate tablet strength for you , depending on your current treatment and your personal risk status . Always take this medicine exactly as your doctor or pharmacist has told you . check with your doctor or pharmacist if you are not sure . you should stay on a cholestrol-lowering diet while taking ZOCOR . Dosage: The recommended dose is ZOCOR 10 mg, 20 mg, or 40 mg by mouth once a day. Adults : The usual starting dose is 10, 20, or , in some cases, 40 mg a day. Your doctor may adjust your dose after at least 4 weeks to a maximum of 40 mg a day. Do not take more than 80 mg a day. Your doctor may prescribe lower doses, particularly if you are taking certainn medicinal products lister above or have certain kidney conditions. The 80 mg dose is only recommended for adult patients with very high cholesterol levels and at high risk of heart disease problems who have not reached their cholesterol goal on lower doses. Use in children and adolescents: For children ( 10 – 17 years old ) , the recommended usssual starting dose is 10 mg a day in the evening. The maximum recommended dose is 40 mg a day. Method of administration: Take ZOCOR in the evening. You can take it with or without food. Keep taking ZOCOR unless your doctor tells you to stop. . if your doctor has prescribed ZOCOR along with another medicine for lowering cholestrol containing any bile acid sequestrant , you should take ZOCOR at least 2 hours before or 4 hours taking the bile acid sequestrant .
OVER-DOSAGE OF ZOCOR 40 14 TAB
If you take more ZOCOR than you should : Please contact your doctor or pharmacist.
CONTRA-INDICATION OF ZOCOR 40 14 TAB
Do not take ZOCOR: if you are allergic (hypersensitive) to simvastatin or any of the other ingredients of this medicine . If you currently have liver problems. If you are pregnant or breast-feeding. If you are taking medicine(s) with one or more than one of the following active ingredients: itraconazole, ketoconazole, posaconazole or voricinazole (used to treat fungal infections). erythromycin, clarithromycin, or telithrpmycin (used to treat infections). HIV protease inhibitors such as indinavir, nelfinavir, ritonavir, and saquinavir (HIV protease inhibitors are used for HIV infections). boceprevir or telaprevir (used to treat hepatitis C virus infection). nefazodone (used to treat depression). cobicistat. gemifibrozil (used to lower cholesterol). ciclosporin (used in organ transplant patients). danazol (a man-made hormone used to treat endometriosis, a condition in which the lining of the uterus grows outside the uterus). if you are taking or, in the last 7 days, have taken or been given a medicine called fusidic acid (used to treat bacterial infection). Do not take more than 40 mg ZOCOR if you are taking lomitapide (used to treat a serious and rare genetic cholesterol condition) Ask your doctor if you are not sure if your medicine is lister above.
STORAGE OF ZOCOR 40 14 TAB
Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date (“EXP”) which is stated on the container. Do not store above 30 °C; avoid transient temperature above 50 °C. Keep blister in outer carton in order to protect from moisture.
PACK OF ZOCOR 40 14 TAB
Carton box containing 1, 2, or 4 (PVC – AL) blisters, each of 7 tablets.
ZOCOR 40 14 TAB MANUFACTURED BY
GLOBAL NAPI PHARMACEUTICALS under license of Merck & Co., Inc., USA and its branches in Netherlands.