Sulbactam sodium (equivalent to 250 mg sulbactam ) ampicillin sodium ( equivalent to 500 mg ampicillin ) + water for injection 2 ml × 1 .

16.00 EGP

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UNICTAM 750TAB; sulbactam, ampicillin , antibacterials .


Sulbactam sodium (equivalent to 250 mg sulbactam ) ampicillin sodium ( equivalent to 500 mg ampicillin ) + water for injection 2 ml × 1 .


ampicillin and sulbactam for injection is indicated for the treatment of infections due of susceptible strains of the designated microorganisms in the conditions listed below . skin and skin structure infections caused by beta – lactamase producing strains of staphylococcus aureus , eschenchia coli , klebsiella spp . ‘( including k. pneumoniae ) , proteus mirabilis , bacteroides fragilis , enterobacter spp , and acinetobacter calcoaceticus ‘ note : for information on use in pediatric patients sections . intra- abdominal infections caused by beta – lactamase producing strains of escherichia coli , klebsiella spp , ( including k . pneumoniae ‘) , bacteroides spp. ( including B . fragilis ) , and enterobacter . gynecological infections caused by beta-lactamase producing strains of escherichia coli , and bacteroides spp . ( including B. fragilis ) . efficacy for this organism in this organ system was stadied in fewer than 10 infections . while ampicillin and sulbactam for injection is indicated only for the conditions listed above , infections caused by ampicillin – susceptible organisms are amenable to treatment with ampicillin – susceptible organisms are also amenable to treatment with ampicillin and sulbactam for injection due to its ampicillin content . therefore , mixed infection infections caused by ampicillin and and sulbactam for injection should not require the addition of another antibiotic . appropriate culture and susceptibility tests should be performed before treatment in order to isolate and identify the organisms causing infection and to determine their susceptibility to ampicillin and sulbactam for injection . therapy may be instituted prior to obtaining the results from bacteriological and suscebility studies , when there is reason to believe the infection may involve any of the beta – lactamase producing organisms listed above in the indicated organ systems , once the results are known , therapy should be adjusted if appropraite . to reduce the development of drug – resistant bacteria and maintain effectiveness of ampicillin and sulbactam for injection and other antibacterial drugs , ampicillin and sulbactam for injection should be used only to treat or prevent infections that proven or strongly suspected to be caused by susceptible bacteria . when culture and suscepitibility information are available . thet should be considered in selecting or modyfying antibacterial therapy . in the absence of such data , local epidermiology and susceptibility patterns may contribute to the empiric selection of therapy .


Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

unictam im/iv can be administered by either intravenous or intramuscular routes . The following dilutions may be used : total dosage : 0.375 : equivalent dosage of sulbactam / ampicillin 0.125-0.25 g : package : 10 ml vial : dilution volume : 0.8 ml : maximum final concentraton :125 -250 mg/ml . – 0.75 g : 0.25 – 0.5 g : 10 ml vial : 1.6 ml : 125-250 mg/ml . – 1.5 g : 0.5-1.5 g : 20 ml vial : 3.2 ml : 125 -250 mg/ml . – 3 g : 1.0-2.0 g : 20 ml vial : 6.4 ml : 125 -250 mg/ml for intravenous administration unictam im/iv should be reconstituted with sterile water for injection or any compatible solution and allowed to sand to allow any foaming to dissipate to permit visual inspection for complete dissolution . the dose can be given by bolus injection over a minimum of 3 minutes or can be used in greater dilutions either as a bolus or as an intravenous infusion over 15-30 minutes . unictam im/iv may also be administered by deep intramuscular injection , if pain experienced , 0.5 % sterile solution for injection of lignocaine hydrochloride anhdrous may be used for reconstitution of the powder . the usual dosage of unictam im/iv is 1.5 g to 12 g per in divided doses every 6 or 8 hours up to a maximum daily dosage of sulbactam of 4 g . less severe infections may be treated on every 12 hours schedule . the dosage of unictam im/iv for most infections in children , infants and nei=onates is 150 mg/kg/day ( corresponding to sulbactam 50 mg /kg /day and ampicillin 100 mg /kg /day ) . in children , infants and neonates dosing is usually every 6 or 8 hours in accordance with the usual practice for ampicillin . in neonates during the first week of life ( espicially preterms ) , dosing is usually every 12 hours . more or less frequent dosing may be indicated depending on the severity of the illness and the renal function of the patient . treatment is usually continued until 48 hours after pyrexia and other abnormal signs have resolved . treatment is normally given given for 5 to 14 days , but the treatment period may be extended or adddditional amicillin may be administered in severly ill cases . in patients with severe impairment of renal function ( creatinine clearance OVER-DOSAGE OF UNICTAM 750TAB


the use of ampicillin and sulbactam for injection is contraindicated in individuals with a history of hypersensitivity reactions to any of the penicillins .


store at a temperature not exceeding 25 c . Protect from light and use immediately after reconstitution . Keep out of reach of children .
375 mg vials contain 0.250gm sulbactam sodium + 0.500 gm ampicillin sodium + one ampoule of 2 ml . Sterile water for injection .
medical union pharmaceuticals ( penicillin plant ) .





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