TARGOFLOXIN 750 MG 10 TAB

80.00 EGP

Each film-coated of Targofloxin 750 mg contains 750 mg of levofloxacin as active substance corresponding to 768.45 mg of levofloxacin hemihydrate.

TARGOFLOXIN 750 MG 10 TAB; levofloxacin, antibacterials .

ACTIVE-INGREDIENT OF TARGOFLOXIN 750 MG 10 TAB

Each film-coated of Targofloxin 750 mg contains 750 mg of levofloxacin as active substance corresponding to 768.45 mg of levofloxacin hemihydrate.

INDICATION OF TARGOFLOXIN 750 MG 10 TAB

Targofloxin tablets are indicated for the treatment of the following infections when due to levoxacin-susceptible microorganisms: Acute bacterial sinusitis. Acute bacterial exacerbations of chronic bronchitis. Community-acquired pneumonia. Complicated urinary tract infections including pyelonephritis. Chronic bacterial prostatis. Skin and soft tissue infections. Septicemia / bacteremia related to the above indications. Intra-abdominal onfections. Uncomplicated urinary tract infections, prostitis.

DOSAGE OF TARGOFLOXIN 750 MG 10 TAB

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

Dosage and route of administration depended on the type and severity of the infection and the sensitivity of the presumed causative pathogen. In cases where initial intravenous treatment with levofloxin solution or infusion has necessary (patients for whom oral administration was inappropriate), it is usually possible to switch to oral route after a few days, according to the conditions of the patient. Given the bioequivalence of the oral and parentral forms, the same dosage can be used. dosage are generally based on the following guidlines for adults: Dosage in patients with normal renal function (creatinine clearance > 50 ml/min) : Acute sinusitis : Unit dose 500 mg (oral, I.V.), Number of doses is 1 every 24 h. Interval between doses 24 h, daily dose ( according to severity ) 500 mg For 10-14 days . Acute exacerbations of chronic bronchitis : Unit dose 250 or 500 mg (oral, I.V.), Number of doses is 1 every 24 h. Interval between doses 24 h, daily dose ( according to severity ) 250 to 500 mg For 7-10 days . community -acquired pneumonia : Unit dose 500 mg (oral, I.V.), Number of doses is 1 or 2 every 24 h. Interval between doses 24 or 12 h, daily dose ( according to severity ) 500 to 1000 mg For 7-14 days. Uncomplicated urinary tract infections: Unit dose 250 mg (oral, I.V.), Number of doses is 1 every 24 h. Interval between doses 24 h, daily dose ( according to severity ) 250 mg For 3 days .complicated urinary tract infections including pyelonephritis : Unit dose 250 mg (oral, I.V.), Number of doses is 1 every 24 h. Interval between doses 24 h, daily dose ( according to severity ) 250** mg For 7-10 days. prostatitis : Unit dose 500 mg (oral, I.V.), Number of doses is 1 every 24 h. Interval between doses 24 h, daily dose ( according to severity ) 500 mg For 28 days. skin and soft tissue infections* :Unit dose 250 or 500 mg (oral, I.V.), Number of doses is 1 or 2 every 24 h. Interval between doses 24 or 12 h, daily dose ( according to severity ) 500 to 1000 mg For 7-14 days. In case of Septicemia / bacteremia: Unit dose 500 mg (oral, I.V.), Number of doses is 1 or 2 every 24 h. Interval between doses 24 or 12 h, daily dose ( according to severity ) 500 to 1000 mg For 10-14 days. In case of Intra-abdominal infections***: Unit dose 500 mg (oral, I.V.), Number of doses is 1 every 24 h. Interval between doses 24 h, daily dose ( according to severity ) 500 mg For 7-14 days. * only for oral administration. ** ( this footnote applies only to solution for infusion ) consideration should be given to increasing the dose in cases of severe infection. *** in combination with an antibiotic with antibiotic with anaerobic coverage. Impaired renal function ( creatinine clearance ≤ 50 ml/min ) . dose regimen : -In case of creatinine clearance (50-20 ml/min ) : first dose is 250 mg : then 125 mg/24 h . Or 500 mg then 250 mg/24 h Or 500 mg then: 250 mg/12 h . -In case of creatinine clearance (19-10 ml/min ): first dose is 250 mg : then 125 mg/48 h . Or 500 mg then 125 mg/24 h Or 500 mg then: 125 mg/12 h . – In case of creatinine clearance (OVER-DOSAGE OF TARGOFLOXIN 750 MG 10 TAB

According to toxicity studies in animals or clinical pharmacology studies performed with supra-therapeutic doses, the most important signs to be expected following acute over dosage of Levoxin tablets are central nervous system symptoms such as confusion, dizziness, impairment of consciousness, and convulsive seizures, increase QT interval as well as gastro-intestinal reactions such as nausea and mucosal erosions. In the event of overdose, symptomatic treatment should be implemented. ECG monitoring should be undertaken , because of the possibility of QT interval prolongation. Antiacids may be used for protection of gastric mucosa. Hemodialysis, including peritoneal dialysis and CAPD, are not effective in removing levofloxacin from the body. No specific antidote exists.

CONTRA-INDICATION OF TARGOFLOXIN 750 MG 10 TAB

Targofloxacin tablets must not be used : in patients hypersensitive to levofloxacin or other quinolones or any of the excipients, in patients with epilepsy, in patients with history of tendon disorders related to fluoroquinolone administration.

STORAGE OF TARGOFLOXIN 750 MG 10 TAB

Store below 30 °C.
PACK OF TARGOFLOXIN 750 MG 10 TAB
Carton box of 2 al/pvc strip contains 5 f.c. tablets and inner insert.
TARGOFLOXIN 750 MG 10 TAB MANUFACTURED BY
GLOBAL NAPI PHARMACEUTICALS 2nd Industrial Zone, 6th of October City, Giza – Egypt www.globalnapi.com

https://www.drugs.com/mtm/levofloxacin.html

https://www.gardeniapharmacy.com/category/medicine-2/

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