Topicals for Hair Loss
Description SPIROMAX F SOLUTION 50ML :
5% Spironolactone and 0.1 Finasteride with synergistic technique that will provide a hair growth stimulant and stop hair shedding process.
5% Spironolactone and 0.1 Finasteride with synergistic technique that will provide a hair growth stimulant and stop hair shedding process.
For Androgenetic alopecia and alopecia areata.
4 puffs twice daily.
Spironolactone acts as an androgen antagonist by competitively blocking androgen receptors, as well as inhibiting ovarian androgen production (15,16).
One particular study conducted in 1988 saw six healthy male patients use a topical spironolactone to a well-defined skin area.
It concluded that the product worked to a local effect without much systemic absorption (17).
However, as this was such a small sample size, I think that it is fair to say that much more research is needed.
I have found that the most common strength used is between 1-3%.
Finasteride works by inhibiting 5AR II enzyme, which is responsible for catalysing the conversion of testosterone to the much more active chemical DHT (14).
A study of 24 healthy males conducted in 2014 evaluated a newly developed finasteride 0.25% topical solution, in comparison to the marketed finasteride 1mg tablet, looking at the movement of drugs within the body and suppressive effects on plasma DHT.
It concluded that a strong and similar inhibition of plasma DHT was found after one week of treatment with both the topical and tablet, albeit finasteride plasma exposure was significantly lower with the topical than with the oral product (18).
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Anonymous (verified owner) –
Good product