Rapamune 1 mg 30 tab
Active Ingredient:
Therapeutic Use of Rapamune 1 mg:
Rapamune is indicated for the prophylaxis of organ rejection in adult patients at low to moderate immunological risk receiving a renal transplant. It is recommended that Rapamune be used initially in combination with ciclosporin microemulsion and corticosteroids for 2 to 3 months. Rapamune may be continued as maintenance therapy with corticosteroids only if ciclosporin microemulsion can be progressively discontinued.
Mechanism of Action:
Sirolimus is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system. Sirolimus inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T- and B-cells. In contrast, tacrolimus inhibits the secretion of IL-2.
Dose of Rapamune 1 mg:
You should not use multiples of 0.5 mg tablets as a substitute for 1 mg and 2 mg tablets, as the
different strengths are not directly interchangeable. You should take Rapamune consistently, either with or without food.
Side Effects of Rapamune 1 mg:
- Fluid collection around the kidney
- Swelling of the body including hands and feet
- Pain
- Fever
- Headache
- Increased blood pressure
- Stomach pain, diarrhoea, constipation, nausea
- Low red blood cells, low blood platelets
- Increased fat in the blood (cholesterol and/or triglycerides)
- Joint pain
- Acne
- Urinary tract infection
- Pneumonia and other bacterial, viral, and fungal infections
- A reduced number of infection-fighting cells in the blood (white blood cells)
- Diabetes
- Abnormal tests of liver function, elevated AST and/or ALT liver enzymes
Read More:
Sirolimus – Mechanism of Action | Mechanism Action | Technology Trends (primidi.com)
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