Rapamune 1 mg 30 tab

Rapamune 1 mg 30 tab

Active Ingredient:

Sirolimus

Therapeutic Use of Rapamune 1 mg: 

Rapamune is indicated for the prophylaxis of organ rejection in adult patients at low to moderate immunological risk receiving a renal transplant. It is recommended that Rapamune be used initially in combination with ciclosporin microemulsion and corticosteroids for 2 to 3 months. Rapamune may be continued as maintenance therapy with corticosteroids only if ciclosporin microemulsion can be progressively discontinued.

Mechanism of Action:

Sirolimus is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system. Sirolimus inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T- and B-cells. In contrast, tacrolimus inhibits the secretion of IL-2.

Dose of Rapamune 1 mg:

You should not use multiples of 0.5 mg tablets as a substitute for 1 mg and 2 mg tablets, as the
different strengths are not directly interchangeable. You should take Rapamune consistently, either with or without food.

Side Effects of Rapamune 1 mg:

•  Fluid collection around the kidney
•  Swelling of the body including hands and feet
•  Pain
•  Fever
•  Headache
•  Increased blood pressure
•  Stomach pain, diarrhoea, constipation, nausea
•  Low red blood cells, low blood platelets
•  Increased fat in the blood (cholesterol and/or triglycerides)
•  Joint pain
•  Acne
•  Urinary tract infection
•  Pneumonia and other bacterial, viral, and fungal infections
•  A reduced number of infection-fighting cells in the blood (white blood cells)
•  Diabetes
•  Abnormal tests of liver function, elevated AST and/or ALT liver enzymes

Read More:

Sirolimus – Mechanism of Action | Mechanism Action | Technology Trends (primidi.com)