Rapamune 1 mg 30 tab

Rapamune is used in the treatment of lymphangioleiomyomatosis; organ transplant, rejection prophylaxis and belongs to the drug class selective immunosuppressant. Risk cannot be ruled out during pregnancy. Rapamune 1 mg is not a controlled substance under the Controlled Substances Act (CSA).

 

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Rapamune 1 mg 30 tab

Active Ingredient:

Sirolimus

Therapeutic Use of Rapamune 1 mg: 

Rapamune is indicated for the prophylaxis of organ rejection in adult patients at low to moderate immunological risk receiving a renal transplant. It is recommended that Rapamune be used initially in combination with ciclosporin microemulsion and corticosteroids for 2 to 3 months. Rapamune may be continued as maintenance therapy with corticosteroids only if ciclosporin microemulsion can be progressively discontinued.

Mechanism of Action:

Sirolimus is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system. Sirolimus inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T- and B-cells. In contrast, tacrolimus inhibits the secretion of IL-2.

Dose of Rapamune 1 mg:

You should not use multiples of 0.5 mg tablets as a substitute for 1 mg and 2 mg tablets, as the
different strengths are not directly interchangeable. You should take Rapamune consistently, either with or without food.

Side Effects of Rapamune 1 mg:

  •  Fluid collection around the kidney
  •  Swelling of the body including hands and feet
  •  Pain
  •  Fever
  •  Headache
  •  Increased blood pressure
  •  Stomach pain, diarrhoea, constipation, nausea
  •  Low red blood cells, low blood platelets
  •  Increased fat in the blood (cholesterol and/or triglycerides)
  •  Joint pain
  •  Acne
  •  Urinary tract infection
  •  Pneumonia and other bacterial, viral, and fungal infections
  •  A reduced number of infection-fighting cells in the blood (white blood cells)
  •  Diabetes
  •  Abnormal tests of liver function, elevated AST and/or ALT liver enzymes

 

Read More:

Sirolimus – Mechanism of Action | Mechanism Action | Technology Trends (primidi.com)

 

 

 

1 review for Rapamune 1 mg 30 tab

  1. yara

    شكرا لتوفير الادوية الناقصه

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