RANI 50MG /2ML 5 AMP; ranitidine, gastrointestinal agents .
ACTIVE-INGREDIENT OF RANI 50MG /2ML 5 AMP
EACH 2 ML CONTAINS : Ranitidine ( as hydrochloride ) 50 mg .
INDICATION OF RANI 50MG /2ML 5 AMP
rani injection is indicated for the treatment of doudonal ulcer , benign gastric ulcer , post-operative ulcer , reflux oesophagitis , zollonger-Ellison syndrome , and the following conditions where reduction of gastric secretion and acid output is desirable : the prophylaxis of gastro-intestinal hemorrhage from stress ulceration in seriously ill patients , the prophylaxis of recurrent hemorrhage in patients with bleeding peptic ulcers and before general anaesthesia in patients considered to be at risk of acid aspiration (mendelson’s syndrome ) , particularly obstetric during labour .
DOSAGE OF RANI 50MG /2ML 5 AMP
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
rani injection may be given either as slow (over a period of at least 2 minutes ) intravenous injection of 50 mg , after dilution to a volume of 20 ml per 50 mg dose , which may be repeated every 6 to 8 hours ; or as an intermittent intravenous infusion at a rate of 25 mg per hours for 2 hours , the infusion may be repeated at 6 to 8 hour intervals or as an intramuscular injection to 50 mg (2 ml ) every six to eight hours . in the prophylaxis of haemorrhage from stress ulceration in seriously ill patients or the prophylaxis of recurrent haemorrhage in patients bleeding from peptic ulceration , parenteral administration may be continued until oral feeding commences . in the prophylaxis of upper gastrointestinal haemorrhage from stress ulceration in seriousely ill patients a priming dose of 50 mg as a slow intravenous injection followed by a continuous intravenous infusion of 0.125 -0.25 mg/kg/hr may be preferred . in patients considered to be risk of developing acid aspiration syndrome . rani injection 50 mg may be given intramuscularly or by slow intravenous injection 45 to 60 minutes before reduction of general anaesthesia . children : the use of rani injection in children has not been evaluated . rani injection has been shown to be compatible with the following intravenous infusion fluids : 0.9 % sodium chloride BP . 5 % dextrose BP . 0.18 % SODIUM CHLORIDE AND 4 % dextrose BP . 4.2 SODIUM Bicarbonate . hartmann’s solution . all unused admixtures of rani injection with infusion fluids should be discarded 24 hours after preparation .
OVER-DOSAGE OF RANI 50MG /2ML 5 AMP
CONTRA-INDICATION OF RANI 50MG /2ML 5 AMP
ranitidine is contraindicated for patients known to have hypersensitivity to the drug .
STORAGE OF RANI 50MG /2ML 5 AMP
keep at temperature (15-30 c ) , away from light . Keep out of the reach of children .
PACK OF RANI 50MG /2ML 5 AMP
a box containing 5 ampoules
RANI 50MG /2ML 5 AMP MANUFACTURED BY
PHARCO B INTERNATIONAL FOR PHARCO PHARMACEUTICALS
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