PRIMPERAN 10 TAB; metoclopramide, antiemetics .
ACTIVE-INGREDIENT OF PRIMPERAN 10 TAB
the active substance is : metoclopramide hydrochloride 10.50 mg ( as anhydrous metoclopramide hydrochloride 10.00 mg ) for one scored tablet .
INDICATION OF PRIMPERAN 10 TAB
adult population : primperan 10 mg scored tablet sare used in adults to : prevent delayed nausea and vomiting that may occur after chemotherapy , prevent nausea and vomiting caused by radiotherapyy , treat nausea and vomiting , including nausea and vomiting which may occur with acute migraine . if the event of migraine , metoclopramide can be taken with oral painkillers to help the painkillers work more effectively . pediatric population : primperan 10 mg scored tablets are indicated in children ( aged 1 to 18 years ) if other treatment does not work or cannot be used to prevent delayed nausea and vomiting that may occur after chemotherapy .
DOSAGE OF PRIMPERAN 10 TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
all indications ( adults patients ) the recommended dose is 10 mg per intake , up to 3 times per day . The maximum recommended daily dose is 30 mg or 0.5 mg /kg . The cmaximum recommended treatment duration is 5 days . Prevention of delayed nausea and vomiting that may occur after chemotherapy ( children aged 1 to 18 years ) . the recommended dose is 0.1 to 0.15 mg/kg , up to 3 times per day , taken by mouth . the maximum daily dose is 0.5 mg / kg . dosing table : -1-3 years : 10 – 14 kg : 1 mg : up to 3 times a day . – 3-5 years : 15 – 19 kg : 2 mg : up to 3 times a day . – 5-9 years : 20-29 kg : 2.5 mg : up to 3 times a day . – 9-18 years : 30-60 kg : 5 mg : up to 3 times a day . – 15-18 years : over 60 kg : 10 mg : up to 3 times a day . . you must take this medicine for more than 5 days to prevent delayed nausea and vomiting that may occur after chemotherapy . primperan 10 mg scored tablets are not suitable for use in children weightening less than 30 kg . other pharmaceutical forms may be more suitable for this patient population . frequency of administration you must wait at least 6 hours between each metoclopramide dose , even if vomiting or rejection of the dose occurs , in orded to avoid overdose . elderly patients : the dose may need to reduced , based on kidney and liver problems , and overall health . other pharmaceutical forms may be more suitable for this patient population . adults with kidney problems : talk to your doctor if you kidney problems . the dose should be reduced if you have moderate or severe kidney disease . other pharmaceutical forms may be more suitable for this patient population . adults with liver problems : talk to your doctor if you have liver problems . the dose should be reduced if you have severe liver disease . other pharmaceutical forms may be more suitable for this patient population . children and adolescents : primperan 10 mg scored tablets must not be used in children aged less than 1 year of age .
OVER-DOSAGE OF PRIMPERAN 10 TAB
contact your doctor or pharmacist straight away . You may experience abnormal movements ( extrapyramidal disorders ) drowsiness , consciousness disorders . Confusion , hallucinations and cardiac disorders , your doctor may prescribe treatment for these symptoms if necessary .
CONTRA-INDICATION OF PRIMPERAN 10 TAB
do not take primperan 10 mg scored tablets if : you are allergic to metoclopramide or any of the other ingredients of this medicine . You have bleeding , obstruction or a tear in the stomach or gut . You have or may have a rare tumor of the adrenal gland , which sits near the kidney ( pheochromocytoma ) . you have ever had involuntary muscle spasms ( tardive dyskinesia ) , when you have been treated with a medicine . you have epilepsy . you have parkinson’s disease . you are taking levodopa ( a medicine used for parkinson’s disease ) or dopamine agonists . you have abnormal levels of a blood pigment ( methemoglobinemia ) in your blood , or have NADH-cytochrome b5 deficiency . do not give primperan 10 mg scored tablets to children under the age of 1 year . do not take primperan 10 mg scored tablets in the cases described above . if you are unsure , talk to your doctor or pharmacist before taking primperan 10 mg scored tablets .
STORAGE OF PRIMPERAN 10 TAB
do not exceed the expiry date listed on the outer packaging . Store at a temperature not exceeding 30 C , in dry place .
PACK OF PRIMPERAN 10 TAB
carton box containing 1 (PVC /AL ) strip contains 10 tablets & inner leaflet .
PRIMPERAN 10 TAB MANUFACTURED BY
sanofi – aventis egypt s.a.e under license of sanofi – aventis / france .