treatment of nocturnal enuresis ( night – time bedwetting ) in patients from the age of 5 after organic disorders of the urinary organs have been excluded : within an overall therapeutic concept , e.g . In cases of failure of other non- medicinal therapies or with indication of a medicinal therapy , vaused by noctural ADH deficiency ( lack of antidiuretic hormone ) . increased , at least twice noctural urination due to increased night – time urine production ( nocturia in connection with nocturnal polyuria ) in adults . trauma – induced polyuria ( overproduction of urine ) and polydipsia ( increased thirst and increased fluid intake ) after hypophysectomy ( disconnection of the pituitary gland ) , after surgery in the pitutery gland area or craniocerebral injury . central diabetes insipidus ( disease characterized by excretion of large amounts of water due to impaired ADH secretion in the brain ; ADH = antidiuretic hormone is a hormone of the pituitary gland that reduces excretion of water ) .

DOSAGE OF MINIRIN MELT 60 MICROGRAM 30TAB

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

always take minirin exactly as your doctor has told you . Check with your doctor or pharmacist if you are not sure . In the event of signs of water retention and / or decreased sodium levels in the blood ( headache , fluid accumul;ation in the tissue , nausea / vomiting , weight gain and , in severe cases , cramps ) treatment should be interrupted until you have fully recovered . when restarting treatment , you must strictly restrict fluid supply . in addition , your doctor will closely monitor blood sodium levelss . special populations : treatment of elderly patients is not recommended . if , nevertheless , your doctor decides for treatment , your blood sodium levels will be monitored on several days before start of treatment . melt tablets with a higher concentration are available for higher and highest doses . the recommended dose is : primary nocturnal enuresis ( night – time bedwetting ) : for the treatment of night – time bedwetting , an initial dosage of 120 micrograms ( 2 minirin melt tablets with 60 micrograms or 1 minirin melt tablets with 120 micrograms ) before going to bed is recommended . in cases of insufficient therapy success , your doctor may increase the dose to 240 micrograms ) . you may not increase the dose without your doctor’s approval . fluid supply should be reduced . the determined effective dose will also be the maintenance dose . it will be determined individually by your doctor and should be used throughout the entire treatment period . duration of adminiestration : after a treatment period of up to 3 months there should be a treatment – free interval of at least 1 week to check whether healing has taken place or whether therapy should be continued . increased night -time voiding ( nocturia ) due to increased urine production during the night : for treatment of increased night urination , the recommended initial dose is 60 micrograms desmopressin ( 1 minirin melt tablet with 60 micrograms ) before going to bed . if this dose is not sufficient after one week , it may be increased up to 120 micrograms ( 2 minirin melt tablets with 60 micrograms or 1 minirin melt tablet with 120 micrograms ) and subsequently to 240 micrograms ( 2 minirin melt tablets with 120 micrograms or q minirin melt tablet with 240 micrograms ) by weekly dose escalations . you should reduce nocturnal fluid supply as far as possible . your doctor will discuss with you the measures required before start of treatment . before start of treatment , you should record the times of urination and the amount of urine for at least 48 hours . in addition , your doctor will measure sodium levels in the blood before start of treatment . you should check your body weight over several days at the begining of treatment and after each dose increase . if adequate effect is not achieved within 1 week with appropriate dosage , the medication should be discontinued . central diabetes insipidus ( disease characterized by excretion of large amounts of large amounts of water due to impaired ADH secretion in the brain ) as well as trauma- induced polyuria , ( overproduction of urine ) and polydipsia ( increased thirst and increased fluid intake ) . adults and children : the daily dose is normally between 120 micrograms ( 2 minirin melt tablets with 60 micrograms or 1 minirin melt tablet with 120 micrograms ) and 720 micrograms ( 3 minirin melt tablets with 240 micrograms ) . treatment should be started with 60 micrograms 3 times daily ( 1 minirin melt tablet with 60 micrograms each ) . the maintenance dose in the most of the patients is 60 – 120 micrograms 3 times daily ( 1-2 minirin melt tablets with 60 micrograms each ) . your doctor will individually adapt the dosage to your response to treatment . method of administration : minirin is placed under the tongue where it dissolves . please consult your doctor or pharmacist , if you believe that the effect of minirin is too strong or too weak .

OVER-DOSAGE OF MINIRIN MELT 60 MICROGRAM 30TAB

special attention should be given to signs of hyperhydration of the body ( water intoxication ) . It may also occur if there is excessive fluid intake at the same time or shortly after the administration of minirin . It manifests by weight gain , headache , nausea , and in severe cases , convulsions sometimes associated with clouding of consciousness up to loss of consciousness . please consult your doctor if you are not sure .

CONTRA-INDICATION OF MINIRIN MELT 60 MICROGRAM 30TAB

minirin must not be used : if you are allergic to desmopression acetate or any of the other ingredients of this medicine . If you are suffering from habitual polydipsia ( habitually increased fluid intake ) or psychogenic polydipsia ( mentally caused increased thirst and increased fluid intake ) if you are suffering from polydipsia and are alcohol – dependant . if you have a known or suspected cardiac insuffieciency . if you have any other disease requiring treatment with diuretics . if you have low sodioum levels in your blood ( hypo natreamia ) . if you have moderate to severe renal insufficiency . if you have conditions with increased ADH secretion ( syndrome of inadequate ADH secretion ) . for the treatment of increased night – time urination if you are 65 or older . excessive fluid intake may lead to retention of water in tissue . in particular in infants under the age of 1 or elderly patients depinding on their general health .

STORAGE OF MINIRIN MELT 60 MICROGRAM 30TAB

do not store above 25 C . Store in the original package in order to protect from moisture .
PACK OF MINIRIN MELT 60 MICROGRAM 30TAB
a white , round melt tablet imprinted with a drop on one side . Is available in packs of 10 , 30 and 90 melt tablets .
MINIRIN MELT 60 MICROGRAM 30TAB MANUFACTURED BY
Catalent U.K. swindon Zydis limited , Frankland road , blagrove , SN5 8RU Swindon , wiltshire , united kingdom .

https://www.webmd.com/drugs/2/drug-12128/desmopressin-oral/details

https://www.gardeniapharmacy.com/category/medicine-2/