LEVEPEX SYRUP; levetiracetam, anticonvulsants .
ACTIVE-INGREDIENT OF LEVEPEX SYRUP
each 1 ml levepex syrup contains : 100 mg levetiracetam .
INDICATION OF LEVEPEX SYRUP
leveapex is indicated as monotherapy : in the treatment of partial onset seizure with or without secondary generalization in patients from 16 years of age with newly diagnosed epilepsy . Levepex is indicated as adjunktive therapy : in the treatment of partial onset seizures with or without secondary generalization in adults and children 4 years of age and older with epilepsy . in the treatment of myoclonic seizures in adults and adolescent from 12 years of age with juvenile myoclonic epilepsy . in the treatment of primary generalized tonic clonic seizures in adults and adolescents from 12 years of age with idiopathic epilepsy .
DOSAGE OF LEVEPEX SYRUP
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
adults 16 years and older : treatment should be initiated withy a daily dose of 1000 mg /day , given in 2 divided doses , additional dosing increments may be given ( 1000 mg/day additional every 2 weeks ) to a maximum recommended daily dose of 3000 mg . levepex is given oraaly with or without food . pediatric patients ages 4 to 80 ml/min : 500 to 1,500 mg : frequancy every 12 h . – mild : creatinine clearance 50-80 ml/min : 500 to 1,000 mg : frequancy every 12 h . – moderate : creatinine clearance 30-50 ml/min : 250 to 750 mg : frequancy every 12 h .- severe : creatinine clearance OVER-DOSAGE OF LEVEPEX SYRUP
somnolence , agitation , aggression , depressed level of consciousness ; respiratory depression and coma were observed with levetiractam overdoses . After an acute overdose the stomach may be emptied by gastric lavage or by induction of emesis . There is no specific antidote for levetiractam . treatment of overdose will be symptomatic and may include hemodialysis . the dialyzer extraction efficiency is 60 % for levetiractam and 74 % for primary metabolite .
CONTRA-INDICATION OF LEVEPEX SYRUP
levetiracetam is contraindicated inj patients with a known hypersensitivity to the product or any of its components .
STORAGE OF LEVEPEX SYRUP
store at temperature between 15 C – 30 C .
PACK OF LEVEPEX SYRUP
glass bottle of 100 ml syrup .
LEVEPEX SYRUP MANUFACTURED BY
MULTIAPEX FOR PHARMACEUTICAL INDUSTRIES – S.A.E.