LETROZOLE 2.5MG 30 TAB; letrozole, hormonal agents .
ACTIVE-INGREDIENT OF LETROZOLE 2.5MG 30 TAB
letrozole tablets for oral administration , containing 2.5 mg of letrozole as nonsteroidal aromatase inhibitor .
INDICATION OF LETROZOLE 2.5MG 30 TAB
letrozole is indicated for the treatment of advanced breast cancer in postmenoposoual women with disease progression following antiestrogen therapy .
DOSAGE OF LETROZOLE 2.5MG 30 TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
adults and elderly patients : the recommended dose of letrozole is one 2.5 mg tablet administrated once day , without regard to meals . Treatment with letrozole should continue until tumor progression is evident . No dose adjustment is required for elderly patients . patients treated with letrozole do not require glucocorticoid or mineralocorticoid replacement therapy . renal impairment : dosage adjustment is required for patients with renal impairment if creatinine clearance is ≥ 10 ml/min . hepatic impairment : no dosage adjustment is recommended for patients with mild to moderate hepatic impairment . patients with severe impairment of liver function should be dosed which causion , because letrozole is eliminated almost exclusively by hepatic metabolism .
OVER-DOSAGE OF LETROZOLE 2.5MG 30 TAB
CONTRA-INDICATION OF LETROZOLE 2.5MG 30 TAB
letrozole is contraindicated in patients with known hypersensitivity to letrozole .
STORAGE OF LETROZOLE 2.5MG 30 TAB
store at 25 ° C , keep out of reach of children
PACK OF LETROZOLE 2.5MG 30 TAB
box of 30 tablets of letrozole 2.5 mg .
LETROZOLE 2.5MG 30 TAB MANUFACTURED BY
JIANGSU HENGRUI MEDICINE CO., LTD.