KEFLEX 500MG TAB; cephalexin, antibacterials .
ACTIVE-INGREDIENT OF KEFLEX 500MG TAB
Each tablet contains, as the active ingredient, cefalexin monohydrate equivalent to 500 mg of cefalexin base.
INDICATION OF KEFLEX 500MG TAB
Cefalexin is a semi-synthetic cephalosporin antibiotic for oral administration. Cefalexin is indicated in the treatment of the following infections due to susceptible micro-organisms: Respiratory tract infections. Otitis media. Skin and soft tissue infections. Bone and joints infections. Genito-urinary tract infections, including acute prostatitis. Dental infections.
DOSAGE OF KEFLEX 500MG TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
Cefalexin is administrated orally. The adult dosage ranges from 1-4 g daily in divided doses; most infections will respond to a dosage of 500 mg every 8 hours. For skin and soft tissue infections, streptococcal pharyngitis, and mild, uncomlicated urinary tract infections, the usual dosage is 250 mg every 6 hours, or 500 mg every 12 hours. For more severe infections or those caused by less susceptible organisms, larger doses may be needed, if daily doses of cefalexin greater than 4 g are required, parenteral cephalosporins, in appropriate doses, should be considered. The elderly and patients with impaired renal function: As for adults: Reduce dosage if renal function is markedly impaired . Children: the usual recommended daily dosage for children is 25-50 mg/kg in divided doses. For skin and soft tissue infections, streptococcal pharyngitis, and mild, uncomlicated urinary tract infections, the total daily dose may be divided and administrered every 12 hours. For most infections, the following schedule is suggested: Children 5 years and over: 250 mg every 8 hours. In severe infections, the dosage may be doubled, In the therapy of otitis media, clinical studies have shown that a dosage of 75 to 100 mg/kg/day in 4 divided doses is required. In the treatment of beta-haemolytic streptococcal infections, a therapeutic dose should be administered for at least 10 days.
OVER-DOSAGE OF KEFLEX 500MG TAB
Symptoms of oral overdose may include nausea, vomiting, epigastric distress, diarrhoea, and haematuria. In the event of severe overdosage, general supportive care is recommended, including close clinical and laboratory monitoring of haematological, renal, and hepatic functions, and coagulation status until the patient is stable. Forced diuresis, peritoneal dialysis, haemodialysis, or charcoal haemoperfusion have not been stablished as beneficial for an overdose of ceflexin. It would be extremely unlikely that one of these procedures would be indicated. Unless 5 to 10 times the normal total daily dose has been ingested, gastro-intestinal decontamination should not be necessary. There have been reports of haematuria, without impairment of renal function, in children accidentally ingesting more than 3.5 g of cefalexin in a day. Treatment has been supportive (fluids) and no sequelae have been reported.
CONTRA-INDICATION OF KEFLEX 500MG TAB
Hypersensitivity to the active substance, to other cephalosporins or to any of the excipients. Previous immediate and/or severe hypersensitivity reaction to a penicillin or to any of other beta-lactam medical products.
STORAGE OF KEFLEX 500MG TAB
Stored at room temperature and away from reach of children.
PACK OF KEFLEX 500MG TAB
Carton box containing 12 F.C. Tablets and inner leaflets.
KEFLEX 500MG TAB MANUFACTURED BY
The Egyptian Co. for Pharmaceutical & Chemical Industries (EPCI)