IPANTEN 50MG CAP; phenytoin, anticonvulsants .
ACTIVE-INGREDIENT OF IPANTEN 50MG CAP
Each one capsule contains 50 mg phenytoin sodium
INDICATION OF IPANTEN 50MG CAP
Simple ( Leave. Jackson seizures) and complex ( I.e. temporal lobe Seizures) partial seizures. Focal seizure and primary generalised tonic clinic seizures ( grand ma1) , sleep epilepsy diffuse epilepsy. Combined epileptic seizures with “grand mal symptoms ” . Seizures prophylaxis and treatment in treatment in cerebral trauma.
DOSAGE OF IPANTEN 50MG CAP
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
The most important goal of treatment is the greatest possible reduction in seizures with respect to both frequency and severity – taking the tolerability of the medication into account. Single – dose quantities and dosing intervals will be determined according to each individual case and according to individual response to medication .. Therefore, a general dosage scheme does not exist. Unless otherwise prescribed, the following regimen is to be observed : adults : if not treated before with any other anticonvulsant 300 mg ipanten a day in 3 doses . This dose can be increased at weekly intervals by 100 mg daily . Adjustment and especially the higher doses should only be prescribed after clinical examination and monitoring plasma concentration .. normally , a daily maintenance dose of 300-40.0 mg is sufficient . rapid saturation in adults : the required saturation level should be performed under clinical conditions and under monitoring of the plasma concentration . oral : 1 g/day , divided into 3 doses (400 mg , 300 mg , 300 mg ) administered at 2 hour intervals . the maintenance dose on day 2 is a total of 300 mg . general dose for children : for gradual dose increases , children up to 12 years are given 2 mg /kg body weight/day .. dosage can be increased every 3 days by 1 mg/kg body weight /day according to , plasma concentration . for rapid saturation level , children older than 6 years may be given 150-200 mg / day starting on day as a maintenance dose ; the dose for children undre 6 is adjusted on the basis of the plasma concentration . the maintenance dose is determined individually according to seizure frequency . side effects and plasma concentration . the usual daily maintenance dose is 4-8 mg/kg body weight . the daily dose should be divided into 2-4 single doses take the capsule with liquid . in every case of medical treatment of epilepsy , it is most important that dosage prescribed by the physician be strictly adhered to and that the patient , under no circumstances , change the dosage or stop the medication even if no further seizers occur . sudden withdrawal may cause accumulation of attacks or status epilepticus . therefore , the dosage should be reduced gradually with gradual introduction of increased doses of a replacement antiepileptic medication . in light of the narrow therapeutic spectrum and differing bioavailabifity of the various application forms of IPANTEN and other phenytoin preparations , a switch should be made only undre , close monitoring of the plasma concentration of panten a constant plasma concentration under steady-state is attained only after 5-14 days .
OVER-DOSAGE OF IPANTEN 50MG CAP
CONTRA-INDICATION OF IPANTEN 50MG CAP
Absolute : – hypersensitivity, to hydantoin. – A-V block grade 11 and 111 . – sick – sinus syndrome. – prior serious damage to blood cells and bone marrow. – within the first three months after myocardial infarction or in case of limited cardiac performance ( left – ventricular ejection fraction less than 35o/o) . Relative : ipanten should be used cautiously in patients with : severe hypotension ( systolic blood pressure < 90 0mg Hg) .. Manifest cardiac insufficiency. A-V block, grade 1 . – sinus bradycardia ( < 5 0 beats / min) . Atrial fibrillation. Atrial flutter. Pulmonary insufficiency. The occurrence of pregnancy in an epileptic patient possess a risk for mother and foetus. Medication will increase the risk, but its use is not excluded. For this reason is women of childbearing age become pregnant or plan to become pregnant she should consult a physician at early pregnancy stages. The physician will then consider all risks and benefits and can decide if further treatment is advisable. Discontinuation of medication on patients own accord is prohibited. In the early stages of pregnancy ( especially between the 20 th and 40 th day of pregnancy) and also after delivery, medication should be checked and the dosage adjusted according to plasma concentration and EEG reading… The lowest seizure – controlling dose should be administered. To decrease Further risks, it is advisable not to combine it with any other medication . Weaning is generally not required but the infant should be monitored for slow weight gain or increased sleep requirement .. To avoid bleeding complications in neonates, prophylactic administ ration of vitamin K 1 is recommended for the mother during the final weeks of pregnancy and for the neonate following delivery. Ipantin should be used with special caution in patients suffering from liver or kidney dysfunction. Regular medical check ups are advisable.
STORAGE OF IPANTEN 50MG CAP
store below 30 C . Keep medication safe and out of children .
PACK OF IPANTEN 50MG CAP
pack of 50 capsules 50 mg and inner leaflet .
IPANTEN 50MG CAP MANUFACTURED BY
ARAB COMPANY FOR GELATINE AND PHARMACEUTICAL PRODUCTS (ARAB CAPS ) .