IMDUR 60 MG 30 TAB; isosorbide mononitrate, cardiovascular agents .
ACTIVE-INGREDIENT OF IMDUR 60 MG 30 TAB
each tablet contains isosorbide-5- mononitrate 60 mg in a prolonged release formulation- durules .
INDICATION OF IMDUR 60 MG 30 TAB
prophylactic treatment of angina pectoris .
DOSAGE OF IMDUR 60 MG 30 TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
60 mg once daily to be taken in the morning . The dose may be increased to 120 mg daily , taken once daily in the morning . The dose can be titrated to minimize the possibility of headache by initiating treatment with 30 mg for the first 2-4 days . The tablets can be taken with or without food . the 60 mg depot tablets are scored and dividable . the whole tablets or if needed the divided halves , should not be chewed or chrushed and should be swallowed together with half aglass of fluid . imdur is not indicated for the relief of acute attacks . in these situations sublingual or buccal nitroglycerine tablets or spray formulatiuons should be used . the matrix of the tablet is isoluble but disintegrates when the active substance is released . occasionally the matrix may pass through the gastrointestinal tract without distintegrating and may be visible in the stool but this does not indicate that the drug has had a reduced effect . children : the safety and efficacy of isosorbide-5-mononitrate modified release tablets have not been established . elderly : no need for routine dosage adjustment in the elderly has been found , but special care may be needed in those with increased susceptibility to hypotension or marked hepatic or renal insufficiency . the lowest effective dose should be used . as with other drugs for the treatment of angina pectoris ; when discontinuing long term treatment , the dosage should be discontinued gradually and the patient should be monitored .
OVER-DOSAGE OF IMDUR 60 MG 30 TAB
symptoms – pulsing headach . More serious symptoms are excitation , flushing , cold perspiration , nausea , vomiting , vertigo , syncope , tachycardia and fall in blood pressure . Management – induction of emesis , activated charcoal . In case of pronounced hypotension the patient should first be placed in the supine position with legs raised . if necessary intravenous administration of fluid .
CONTRA-INDICATION OF IMDUR 60 MG 30 TAB
hypersensitivity to the active substance or to any of the excipients , shock , hypotension , constrictive cardiomyopathy and pericarditis . Patients treated with imdur must not be given phosphodiesterase type 5 inhibitors (e.g. slidenafil) .
STORAGE OF IMDUR 60 MG 30 TAB
do not store above 30 C .
PACK OF IMDUR 60 MG 30 TAB
box of 30 tablets .
IMDUR 60 MG 30 TAB MANUFACTURED BY
AstraZeneca.
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