GLEMPOZIN 10MG 30 TAB

144.00 EGP

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GLEMPOZIN 10MG 30 TAB

GLEMPOZIN 10MG 30 TAB

ACTIVE INGREDIANT GLEMPOZIN 10MG 30 TAB

empagliflozin 10 mg

WHY TO USE

It is a medicine to reduce blood sugar levels for patients with type 2 diabetes… and to treat patients with heart failure.
Empagliflozin is also used in patients with type 2 diabetes and heart disease to reduce the risk of death from a heart attack or stroke.

 

Empagliflozin is an orally active, selective inhibitor of SGLT2 with a bioavailability of 78%, no active metabolites, and very limited drug-drug interactions.
Empagliflozin inhibited reabsorption of up to 40% of filtered glucose at single daily doses of 0.5 mg to 10 mg, rising to 40% to 60% inhibition of filtered glucose at higher doses and reaching a plateau at around the 100-mg dose. When empagliflozin was administered with food, there were no relevant effects on UGE. The mean cumulative UGE was 71.7 g in a fasting state compared with 75.9 g in a fed state with the 50-mg empagliflozin dose over 24 hours following oral administration. All doses of empagliflozin exhibited higher amounts of glucose excretion when compared with placebo in the single rising-dose study.
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