EPIRIZINE 10MG 10 TAB

Each F.C. Tablet contains: Cetirizine dihydrochloride 10 mg.

9.00 EGP

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EPIRIZINE 10MG 10 TAB; cetrizine, respiratory tract agents .

ACTIVE-INGREDIENT OF EPIRIZINE 10MG 10 TAB

Each F.C. Tablet contains: Cetirizine dihydrochloride 10 mg.

INDICATION OF EPIRIZINE 10MG 10 TAB

In adults and paediatric patients 2 years and above: Epirizine is indicated for the relief of nasal and ocular-symptoms of seasonal and pereennial rhinitis. Epirizine is indicated for the relief of symptoms of chronic idiopathic urticaria.

DOSAGE OF EPIRIZINE 10MG 10 TAB

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

Children aged from 2 to 6 years: 2.5 – 5 mg daily. Children aged above 6 years: 5 mg – 10 mg daily. Adults and Adolescents over 12 years of age: 10 mg once daily. The tablets need to be swallowed with a glass of liquid. Elderly: Data do not suggest that the dose needs to be reduced in elderly subjects provided that the renal function is normal. Patients with moderate to severe renal impairment: There is no data to document the efficacy/safety ration in patients with renal impairment. Since cetirizine is mainly excreted via renal route, in case no alternative treatment can be used, the dosing intervals must be individualized according to renal function . Refer to the following table and adjust the dose as indicated. To use this dosing table, an estimate of the patient’s creatinine clearance [CLcr] in ml/min is needed. Dosing adjustments for adult patients with impaired renal function: In case of Normal creatinine clearance ≥ 80 ml/min : Dosage is 10 mg once daily. In case of Mild creatinine clearance 50-79 ml/min : Dosage is 10 mg once daily. In case of Moderate creatinine clearance 30-49 ml/min : Dosage is 5 mg once daily. In case of Severe creatinine clearance OVER-DOSAGE OF EPIRIZINE 10MG 10 TAB

Symptoms: symptoms observed after an overdose of cetirizine are mainly associated with CNS effects or with effects that could suggest an anticholinergic effect. Adverse events reported after an intake of at least 5 times the recommended daily dose are: confusion, diarrhoea, dizziness, fatigue, headache, malaise, mydriasis, pruritis, restlessness, sedation, somnolence, stupor, tachycardia, tremor and urinary retention. Management: Should overdose occur, symptomatic or supportive treatment is recommended. Gastric lavage should be considered following ingestion of a short occurrence. There is no known specific antidote to cetirizine. Cetirizine is not effectively removed by dialysis.

CONTRA-INDICATION OF EPIRIZINE 10MG 10 TAB

Hypersensitivity to the active substance, to any of the excipients, to hydroxyzine or to any piperazine derivative. Patients with severe renal impairment at less than 10 ml/min creatinine clearance . Patients with rare hereditary proplems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take Epirizine film-coated tablets.

STORAGE OF EPIRIZINE 10MG 10 TAB

Store in a dry place at a temperature not exceeding 30°C.
PACK OF EPIRIZINE 10MG 10 TAB
Box of one strip [Al/transparent PVC] of 10 F.C. Tablets and insert leaflet.
EPIRIZINE 10MG 10 TAB MANUFACTURED BY
EGYPTIAN INT. PHARMACEUTICAL INDUSTRIES CO. E.I.P.I.CO. TENTH OF RAMADAN CITY A.R.E.

https://www.webmd.com/drugs/2/drug-12065/cetirizine-oral/details

https://www.gardeniapharmacy.com/category/medicine-2/

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