For the treatment of the following infections when due to susciptible microorganisms: – upper and lower respiratory tract infections. – skin and soft tissue infections. – urinary tract infections. – other infections: osteomyelitis and septic arthritis.

DOSAGE OF DURICEF 500MG SUSP

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

Cefadroxil monohydrate is acid stable and may be administrated orally without regard to meals. Administration with food may be helpful in diminishing potential gastrointestinal complaints occassionally associated with oral cephalosporin therapy. Route of Adiministration: For oral use. Adults: Urinary tract infections: For uncomplicated lower urinary tract infections (i.e.,cystitis) the usual dosage is 1 or 2 gm per day in a single dose or in two equally divided doses. For all other urinary tract infections the usual dosage is 1 g per day in a single dose or in two equally divided doses. Skin and skin structure infections: For skin and skin structure infections the usual dosage is 1 g per day in a single dose or in two equally divided doses. Pharyngititis and tonsillitis: For Group A beta-hemolytic streptococcal pharyngitis and tonsillitis, the usual dosage is 1 g per day in a single dose or in two equally divided doses for 10 days. Upper and lower respiratory tract infections: For mild infections the usual dosage is 1 g per day in a single dose or in two equally divided doses. For moderate to severe infections the recommended dosage is 1 g to 2 gm daily in two equally divided doses. Children: The recommended dosage for children is 25 to 50 mg/kg/day in two equally divided doses(every 12 hours) as indicated. For pharyngitis, tonsillitis and impetigo the recommended daily dosage may be administerated as a single dose or in two equally divided doses (every 12 hours). DURICEF ORAL SUSPENSION (dose q12h) : Child’s weight In case of 10 kg 1.250-2.5 ml. 15 kg 1.875-3.75 ml. 20 kg 2.5-5 ml. 25 kg 3.125-6.25 ml. Elderly : No specific doasage recommendations for precautions for use in the elderly except monitoring of patients with impaired renal function. Renal impairment : In patients with renal insufficiency ( creatinine clearance / = Initial dose is 1 g Maintainance dose is 500 mg Administration interval 36 hours. Clinic trials with 5 anuric patients have shown that after an oral dosage of 1 g approximately 63% of the dose will be excreted during hemodialysis of 6 to 8 hours.

OVER-DOSAGE OF DURICEF 500MG SUSP

Symptoms and signs of overdose may intensify the adverse effects, especially in patients prone to gastrointestinal disorders. Treatment : No antidote exists and treatment should be symptomatic. For absorbtion of quantities greater than 250 mg/kg, it is recommended to perform emesis induction.

CONTRA-INDICATION OF DURICEF 500MG SUSP

Cefadroxil is contraindicated in: – Hypersensitivity to the active substance , to other cephalosporins, or to any of the excipents. Previous immediate and/or severe hypersensitivity reaction to a penicillin or to any other beta-lactam medicinal products.

STORAGE OF DURICEF 500MG SUSP

The dry powder is stored at temperature 15°- 30°C.
PACK OF DURICEF 500MG SUSP
Carton box of 60 ml and inner leaflet.
DURICEF 500MG SUSP MANUFACTURED BY
Smithkine Beecham Egypt L.L.C. An affiliated co. to GalaxoSmithkline.

https://www.webmd.com/drugs/2/drug-1756/cefadroxil-oral/details

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