diavance is indicated in the following conditions : – as initial therapy ( adjunct to diet and exercise ) to improve glycemic control in patients with type 2 diabetes whose hyperglycemia cannot be satisfactorily managed with diet and exercise alone . – as second-line therapy when diet , exercise and initial treatment with a sulfonylurea or metformin alone dose not result in adequate glycemic control in patients with type 2 diabetes . – for patients requiring additional therapy , a thiazolidinedione may be added to diavance to achieve addditional glycemic control .

DOSAGE OF DIAVANCE 2.5MG 30TAB

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

general considerations : diavance should be given with meals . Diavance shouldd initiated at a low dose , with gradual dose escalation as described below . With initial treatment and during dose titration , appropriate blood glucose monitoring should be used to determine the therapeutic response to diavance and to identify the minimum effective dose for the patient. thereafter , HbA1c ( glycosylated hemoglobin ) should be measured at intervals of approximately 3 months to assess the effectiveness of therapy . initial therapy : recommended starting dose : one tablet ( 1.25 mg / 250 mg ) once or twice ddaily with morning and evening meals . dosage increases should be made in increments of 1.25 / 250 mg per day every 2 weeks up to the maximum effective dose necessary to acheive adequate control of blood glucose . secondd line therapy : recommended starting dose : one tablet ( 2.5 mg / 500 mg ) or ( 5 mg / 500 mg ) twice daily with morning and evening meals . addition of thiazolidinediones to diavance therapy : when a thiazolidineddione is addedd to diavance therapy , the current dose of diavance can be continued and the thiazolidineddione is initiatedd at its recommended ddose .

OVER-DOSAGE OF DIAVANCE 2.5MG 30TAB

CONTRA-INDICATION OF DIAVANCE 2.5MG 30TAB

known hypersensitivity to metformoin HCL or glyburide . Acute or chronic metabolic acidosis , including diabetic ketoacidosis , with or without coma . Congestive heart failure requiring pharmacologic treatment . Renal diseases or renal dysfunction which may also result from conditions such as cardiovascular collapse ( shock ) , acute myocardial infarction , and septicemia .