CELEBREX 200MG 15CAP

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Description

CELEBREX 200MG 15CAP; celecoxib, anti inflammatory agents .

ACTIVE-INGREDIENT OF CELEBREX 200MG 15CAP

Each capsule contains: 200 mg Celecoxib.

INDICATION OF CELEBREX 200MG 15CAP

CELEBREX is indicated: 1.1 Osteoarthritis (OA): For the management of the signs and symptoms of OA. 2.2 Rheumatoid Arthritis (RA): For the management of the signs and symptoms of RA. 1.3 juvenile Rheumatoid Arthritis (JRA): For the management of the signs and symptoms of JRA in patients 2 years and older. 1.4 Ankylosing Spondylitis (AS): For the management of the signs and symptoms of AS. 1.5 Acute Pain: For the management of acute pain in adults. 1.6 Primary Dysmenorrhea: For the management of Primary Dysmenorrhea.

DOSAGE OF CELEBREX 200MG 15CAP

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

Carefully consider the potential benefits and risks of CELEBREX and other treatment options before deciding to use CELEBREX. Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. These doses can be given without regard to timing of meals. 2.2 Osteoarthritis: For OA, the dosage is 200 mg per day administered as a single dose or as 100 mg twice daily. 2.3 Rheumatoid Arthritis: For RA, the dosage is 100 to 200 mg twice daily. 2.4 juvenile Rheumatoid Arthritis: For JRA, the dosage for pediatric patients (age 2 years and older) is based on weight. For patients > 10 kg to < 25 kg the recommended dose is 50 mg twice daily. For patients > 25 kg the recommended dose is 100 mg twice daily. For patients who have difficulty swallowing capsules, the contents of a CELEBREX capsule can be added to applesauce. The entire capsule contents are carefully emptied onto a level teaspoon of cool or room temperature applesauce and ingested immediately with water. The sprinkled capsule contents on applesauce are stable for up to 6 hours under refrigrated conditions ( 2-8 °C/35-45 °F). 2.5 Ankylosing Spondylitis : For AS, the dosage of CELEBREX is 200 mg daily in single (once per day) or divided (twice per day) doses. If no effect is observed after 6 weeks, a trial of 400 mg daily may be worthwhile, If no effect is observed after 6 weeks on 400 mg daily, a response is not likely and consideration should be given to alternate treatment options. 2.6 the management of acute pain and treatment of Primary Dysmenorrhea: For management of acute pain and treatment of primary dysmenorrhea, the dosage is 400 mg initially, followed by an additional 200 mg dose if needed on the first day. On subsequent days, the recommended dose is 200 mg twice daily as needed. 2.7 Special populations: Hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh class B), reduce the dose by 50% . The use of CELEBREX in patients with severe hepatic impairment is not recommended. Poor Metabolizers of CYP2C9 Substrates: In adult patients who are known or suspected to poor CYP2C9 metabolizers based on genotype or previous history/experience with other CYP2C9 substrates (such as warfarin , phenytoin), initiate treatment with half of the lowest recommended dose. In patients with JRA who are known or suspected to be poor CYP2C9 metabolizers, consider using alternative treatments.

OVER-DOSAGE OF CELEBREX 200MG 15CAP

Symptoms following acute NSAID overdosages have been typically limited to lethergy, drowsiness, nausea, vomiting, and epigastric pain, which have been generally reversible with supportive care. Gastrointestinal bleeding has occurred. Hypertension, acute renal failure, respiratory depression, and coma have been occured, but were rare. No overdoses of CELEBREX were reported during clinical trials. Doses up to 2400 mg/day for up to 10 days in 12 patients did not result in serious toxicity. No information is available regarding the removal of celecoxib by hemodialysis, but based on its high degree of plasma protein binding (> 97%) dialysis is unlikely to be useful in overdose. Manage patients with symptomatic and supportive care following an NSAID over dosage . There is no specific antidotes. Consider emesis and/or activated charcoal (60 to 100 grams in adults, 1 to 2 grams per kg of body weight in pediatric patients) and/or osmotic cathartic in symptomatic patients seen within four hours of ingestion or in patients with a large over dosage ( 5 to 10 times the recommended dosage ), Forced diuresis, alkalinization of urine, hemodialysis, or hemoperfusion may not be useful due to high protein binding.

CONTRA-INDICATION OF CELEBREX 200MG 15CAP

CELEBREX is contraindicated in the following patients: Known hypersensitivity (e.g. anaphylactic reactions and serious skin reactions) to celecoxib, any components of the drug product. History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs, severe, sometimes fatal, anaphylactic reactions to NSAIDs, have been reported in such patients. In the setting of coronary artery bypass graft (CABG) surgery. In patients who have demonstrated allergic-type reactions to sulfonamides.

STORAGE OF CELEBREX 200MG 15CAP

Store at temperature not exceeding 30 °C in a dry place.
PACK OF CELEBREX 200MG 15CAP
3 Blisters each of 5 capsules.
CELEBREX 200MG 15CAP MANUFACTURED BY
Pfizer Egypt.

https://www.drugs.com/celecoxib.html

https://www.gardeniapharmacy.com/category/medicine-2/

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Reviews (1)

1 review for CELEBREX 200MG 15CAP

  1. Anonymous (verified owner)

    Good with no side effects

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