Carbapex is indicated in epilepsy, complex or simple partial seizures (with or without loss of consciousness ) with or without secondary generalization; generalized tonic clonic seizures, and mixed form of seizures. Carbapex is usually not effective in absence (petit mal) and myoclonic seizures. Carbapex is suitable for both monotherapy and combination therapy. Carbapex is indicated in acute mania and maintenance treatment of bipolar affective disorders to prevent or attenuate recurrence . Carbapex is indicated in idiopathic trigeminal neuralgia due to multiple sclerosis (either typical or atypical). Carbapex is indicated in painful diabetic neuropathy, alcohol withdrawal syndrome, idiopathic glosspharyngeal neuralgia and diabetes insipidus centralis.

DOSAGE OF CARBAPEX CR 400MG 30TAB

Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet

Ask your pharmacist or doctor for help if you do not understand the instructions on the box .

The recommended dose is : –

Carbapex tablets may be taken during, after or between meals. Epilepsy: Carbapex treatment should be initiated with a low daily dosage, to be slowly increased until an optimal effect is obtained. When Carbapex is added to existing anti-epileptic therapy, this should be done gradually while maintaining, or adapting, the dosage of the other anti-epileptic(s). Adults: Initially 100-200 mg once or twice daily. Slowly raise the dosage of Carbapex until generally 400 mg 2-3 times daily or until an optimum response is obtained. In some patients, 1600 mg or even 2000 mg daily may be appropriate. Children: Children over 4 years of age will start with 100 mg/day of Carbapex, increasing at weekly intervals by 100 mg. Maintenance dosage: 10-20 mg/kg body weight daily, i.e. 4-5 years of age : 200-400 mg daily. 6-10 years of age : 400-600 mg daily. 11-15 years of age : 600-1000 mg daily. Dosage should be given in intervals of 6-8 hours to minimize fluctuations in plasma concentration. Trigeminal neuralgia: Slowly raise the initial dosage of 200-400 mg daily of Carbapex until freedom from pain is achieved (normally at 200 mg 3-4 times daily ). Then gradually reduce the dosage of Carbapex to the lowest possible maintenance level. In elderly patients, and initial dose of 100 mg daily is recommended. Painful diabetic neuropathy: Average dosage: 200 mg 2-4 times daily. Acute mania and maintenance treatment of bipolar disorders: Dosage range: about 400-1600 mg daily of Carbapex, the usual dosage being 400-600 mg daily given in 2-3 divided doses. In acute mania, the dosage should be increased rather quickly, whereas small dosage increments are recommended for maintenance therapy of bipolar disorders in order to provide optimal tolerability.

OVER-DOSAGE OF CARBAPEX CR 400MG 30TAB

CONTRA-INDICATION OF CARBAPEX CR 400MG 30TAB

Known hypersensitivity to carbamazepine or structurally related drug ( e.g. tricyclic antidepressants) or any other component of the formulation. Patients with atrioventricular block, a history of bone marrow depression, or a history of acute intermittent porphyria. Because it is structurally related to tricyclic antidepressants the use of carbamazepine is not recommended in combination with mono-amineoxidase inhibitors (MAOIS); before administering carbamazepine, MAOIS should be discontinued for a minimum of 2 weeks, or longer if the clinical situation permits.

STORAGE OF CARBAPEX CR 400MG 30TAB

PACK OF CARBAPEX CR 400MG 30TAB
Pack of 30 tablets.
CARBAPEX CR 400MG 30TAB MANUFACTURED BY
Multi-Apex for Pharmaceutical Industries – S.A.E. – Badr City – Cairo – Egypt.

https://www.webmd.com/drugs/2/drug-1493-5/carbamazepine-oral/carbamazepine-oral/details#:~:text=Carbamazepine%20is%20used%20to%20prevent,(such%20as%20trigeminal%20neuralgia).

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