BURINEX TAB; bumetanide, cardiovascular agents .
ACTIVE-INGREDIENT OF BURINEX TAB
Tablets: Bumetanide 1 mg.
INDICATION OF BURINEX TAB
BURINEX is indicated whenever diuretic therapy is required in the treatment of oedema e.g. associated with congestive heart failure, cirrhosis of the liver, renal diseases including the nephrotic syndrome. Acute pulmonary oedema, drug-induced fluid retention, and drug poisoning that can be treated by forced diuresis. Hypertension.
DOSAGE OF BURINEX TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
Orally : 1 tablet daily. In refractory cases the dose can be increased gradually till a satisfactory response has been obtained. Rarely it will be necessary to exceed a dose of 4 mg daily. The 5 mg tablet is for use in resistant oedema due to renal insufficiency and where higher doses are required. In high dose therapy consideration should be given to a twice daily dosing. Children: The dose is calculated on the basis of 0.03 – 0.06 mg / kg daily. Elderly: Adjust dosage according to response: a dose of 0.5 mg daily may be sufficient in some elderly patients.
OVER-DOSAGE OF BURINEX TAB
General measures should be taken to restore blood volume, maintain blood pressure and correct electrolyte disturbance.
CONTRA-INDICATION OF BURINEX TAB
Although BURINEX can be used to induce diuresis in renal insufficiency, any marked increase in blood urea or the development of oliguria or anuria during treatment of severe progressing renal disease are indications for stopping treatment with BURINEX. BURINEX is contraindicated in hepatic coma and care should be taken in states of severe electrolyte depletion. As with other diuretics, BURINEX should not be administered concurrently with lithium salts. Diuretics can reduce lithium clearance resulting in high serum levels of lithium.
STORAGE OF BURINEX TAB
PACK OF BURINEX TAB
BURINEX TAB MANUFACTURED BY
MINAPHARM Under Licence of : LEO PHARMACEUTICAL BALLERUP-DENMARK.