ASPOCID INF 30TAB

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Description

ASPOCID INF 30TAB

Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI).

 

Active Ingredient of Aspocid

acetylsalicylic acid (ASA)

 

What is Acetylsalicylic acid ?

  • Acetylsalicylic acid (ASA) treats pain and fever due to various causes.
  • Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI).
  • Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer.
  • Aspirin is classified as a non-selective cyclooxygenase (COX) inhibitor and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others.
  • Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants

 

 

Indications of Aspocid Infants

Pain, fever, and inflammation

  • Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries.
  • It relieves symptomatic pain relief after surgical and dental procedures.
  • The extra strength formulation of acetylsalicylic acid is also for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound).
  • ASA inhibits platelet aggregation.
  • Reduces the risk of cardiovascular death in suspected cases of myocardial infarction (MI).
  • Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction.
  • For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments).
  • prevents of thromboembolism after hip replacement surgery.
  • decreases platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA).
  • Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site.

 

Mechanism of action

  • Acetylsalicylic acid (ASA) blocks prostaglandin synthesis. It is non-selective for COX-1 and COX-2 enzymes. Inhibition of COX-1 results in the inhibition of platelet aggregation for about 7-10 days (average platelet lifespan).
  • The acetyl group of acetylsalicylic acid binds with a serine residue of the cyclooxygenase-1 (COX-1) enzyme, leading to irreversible inhibition.
  • This prevents the production of pain-causing prostaglandins. This process also stops the conversion of arachidonic acid to thromboxane A2 (TXA2), which is a potent inducer of platelet aggregation.
  • Platelet aggregation can result in clots and harmful venous and arterial thromboembolism, leading to conditions such as pulmonary embolism and stroke.
  • It is important to note that there is 60% homology between the protein structures of COX-1 and COX-2. ASA binds to serine 516 residue on the active site of COX-2 in the same fashion as its binding to the serine 530 residue located on the active site of COX-1.
  • The active site of COX-2 is, however, slightly larger than the active site of COX-1, so that arachidonic acid (which later becomes prostaglandins) manages to bypass the aspirin molecule inactivating COX-2. ASA, therefore, exerts more action on the COX-1 receptor rather than on the COX-2 receptor. A higher dose of acetylsalicylic acid is required for COX-2 inhibition.

 

Side effects of Aspocid Infants 

  • stomach or gut irritation
  • indigestion
  • nausea
  • worsening asthma symptoms
  • vomiting
  • stomach inflammation
  • stomach bleeding
  • bruising

 

Is aspocid safe for children?

Doctors do not usually recommend aspirin for people under 18.

This is because it can increase the risk of a serious condition called Reye’s syndrome, which can appear after a viral infection such as a cold, the flu, or chickenpox. Reye’s syndrome can lead to permanent brain injury or death.

However, a clinician may prescribe aspirin to a child under supervision if they have Kawasaki disease or to prevent blood clots from forming after heart surgery.

For children, doctors usually recommend paracetamol or ibuprofen, in appropriate doses, instead of aspirin.

 

Risks and precautions

People with the following conditions should be cautious about taking aspirin, and should only do so if a doctor recommends it:

  • bleeding disorders, such as hemophilia
  • uncontrolled high blood pressure
  • asthma
  • peptic or stomach ulcers
  • liver or kidney disease

 

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Reviews (1)

1 review for ASPOCID INF 30TAB

  1. mariam (verified owner)

    Very sweet in blood thinners

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