ADANCOR 10 MG 30 TAB; nicorandil, cardiovascular agents .
ACTIVE-INGREDIENT OF ADANCOR 10 MG 30 TAB
Nicorandil (DCI) 10 mg .
INDICATION OF ADANCOR 10 MG 30 TAB
adancor is indicated in adults for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled or have a contraindication or intolerance to first – line antianginal therapies ( such as beta – blockers and / or calcium antagonists ) .
DOSAGE OF ADANCOR 10 MG 30 TAB
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
The recommended dose is : –
the usual therapeutic range is 10 to 20 mg twice daily . the usual starting dose is 10 mg twice daily (bid) , in the morning and in the evening preferably . It is recommended to gradually increase the dose in accordance with the patient’s needs , response and tolerance up to 40 mg twice daily , if necessary . a lower starting dose of 5 mg twice daily may be used in patients particularly prone to headache . – elderly there are no special dosage for elderly patients , but as with all medicines , the use of the lowest effective dose is recommended . patients with liver and / or renal impairment . there are no special dosage for patients with liver and/or renal impairment . paediatric population : adancor is not recommended in paediatric patients since its safety and efficacy have not been established in this patients group . adancor is administered by oral route . the tablets are to be swallowed in the morning and in the evening as a whole with some liquid . administration is independent from food intake .
OVER-DOSAGE OF ADANCOR 10 MG 30 TAB
symptoms : in case of acute overdose , the exceeded symptomatology may be peripheral vasodilation with a drop in blood pressure and reflex tachycardia . – management : monitoring of cardiac function and general supportive measures are recommended . If not successful , increase in circulating plasma volume by substitution of fluid is recommended . in life threating situations , administration of vasopressors must be considered .
CONTRA-INDICATION OF ADANCOR 10 MG 30 TAB
hypersensitivity to Nicorandil or to any of the excipients . – patients with shock ( including cardiogenic shock ) , severe hypotension , or left venticular dysfunction with low filling pressure or cardiac decompensation .- use of phosphodiesterase 5 inhibitors , since this can lead to a serious drop in blood pressure . – use of soluble guanylate cyclase stimulator (s) ( such as riociguat ) since itt can lead to a serious drop in blood pressure . – hypovololaemia . – acute pulmonary edema .
STORAGE OF ADANCOR 10 MG 30 TAB
srore at temperature not exceeding 25 ° C . In a dry place . Store in the original package to protect from moisture .
PACK OF ADANCOR 10 MG 30 TAB
box of 30 .
ADANCOR 10 MG 30 TAB MANUFACTURED BY
Merck KGaA ., Frankfurter Strasse 250 , 64293 Darmstadt , Germany .
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